| 不同生长年限云南重楼药材质量比较研究 |
| 投稿时间：2022-08-22 点此下载全文
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| 引用本文：王璇,贾天颖,珍桑拉姆,徐文娟,李春帅,杨琳琳,张姝妍,文佳,程水清,王旭星,徐新房,李向日.不同生长年限云南重楼药材质量比较研究[J].中国现代中药,2022,24(12):2450-2454 |
| DOI：10.13313/j.issn.1673-4890.20220822001 |
| 摘要点击次数: 113 |
| 全文下载次数: 0 |
| 作者中文名 | 作者英文名 | 单位中文名 | 单位英文名 | E-Mail |
| 王璇 |
WANG Xuan |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 贾天颖 |
JIA Tian-ying |
北京市同仁堂股份有限公司 同仁堂制药厂，北京 102629 |
Tongrentang Pharmaceutical Factory of Beijing Tongrentang Co., Ltd., Beijing 102629, China |
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| 珍桑拉姆 |
ZHEN Sang-la-mu |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 徐文娟 |
XU Wen-juan |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 李春帅 |
LI Chun-shuai |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 杨琳琳 |
YANG Lin-lin |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 张姝妍 |
ZHANG Shu-yan |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 文佳 |
WEN Jia |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 程水清 |
CHENG Shui-qing |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 王旭星 |
WANG Xu-xing |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 徐新房 |
XU Xin-fang |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 李向日* |
LI Xiang-ri |
北京中医药大学 中药学院/北京市中药品质评价重点实验室，北京 102488 |
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing 102488, China |
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| 基金项目:国家中药标准化项目（ZYBZH-Y-YN-44）；国家药典委员会标准制修订研究项目（2018Z006） |
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| 中文摘要:目的 基于性状鉴别、浸出物及含量测定研究，评价不同生长年限云南重楼药材质量。方法 采用传统经验鉴别药材外观性状，运用热浸法测定药材醇溶性浸出物含量，采用高效液相色谱法对样品中重楼皂苷Ⅰ、重楼皂苷Ⅱ、重楼皂苷Ⅲ、重楼皂苷Ⅳ、重楼皂苷Ⅴ、重楼皂苷Ⅵ、重楼皂苷Ⅶ、重楼皂苷D和重楼皂苷H的含量进行测定。结果 不同生长年限云南重楼药材外观性状、浸出物、有效成分含量差异较大。随着生长年限的增加，云南重楼药材单个质量、直径及体积明显增加；8年生云南重楼药材醇溶性浸出物质量分数最高；就药材的有效成分含量而言，7年生药材9种重楼皂苷总质量分数最高。结论 综合性状鉴别、浸出物及含量测定结果，最终初步确定云南重楼以7年生药材质量为最佳。 |
| 中文关键词:云南重楼 生长年限 含量测定 质量研究 |
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| Comparison of the Quality of Paridis Rhizoma in Different Growth Years |
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| Abstract:Objective To evaluate the quality of Paridis Rhizoma in different growth years based on character identification, extraction, and content determination.Methods The appearance characters of Paridis Rhizoma were identified by traditional experience. The content of alcohol-soluble extracts was determined by the hot dipping method, and the content of polyphyllins Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ, Ⅵ, Ⅶ, D, and H in Paridis Rhizoma samples was determined by high-performance liquid chromatography (HPLC).Results There were significant differences in the appearance characters, extracts, and content of active components of Paridis Rhizoma in different growing years. With the increase in growth years, the individual weight, diameter, and volume of Paridis Rhizoma increased obviously. The content of alcohol-soluble extracts of 8-year-old Paridis Rhizoma was the highest. In terms of the content of active components in Paridis Rhizoma, the total content of polyphyllins Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ, Ⅵ, Ⅶ, D, and H in 7-year-old Paridis Rhizoma was the highest.Conclusion Based on the results of character identification, extraction, and content determination, it is preliminarily determined that 7-year-old Paridis Rhizoma has the optimal quality. |
| keywords:Paridis Rhizoma growth years content determination quality research |
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