多指标权重分析法结合正交试验优选醋五灵脂炮制工艺
投稿时间:2022-02-16     点此下载全文
引用本文:李玲,彭致铖,严玉晶,邝敏,林嘉明,蔡盛康,张正.多指标权重分析法结合正交试验优选醋五灵脂炮制工艺[J].中国现代中药,2022,24(12):2455-2461
DOI:10.13313/j.issn.1673-4890.20220216004
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作者中文名作者英文名单位中文名单位英文名E-Mail
李玲 LI Ling 广东一方制药有限公司 广东省中药配方颗粒企业重点实验室,广东 佛山 528244 Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China  
彭致铖 PENG Zhi-cheng 广东一方制药有限公司 广东省中药配方颗粒企业重点实验室,广东 佛山 528244 Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China  
严玉晶 YAN Yu-jing 广东一方制药有限公司 广东省中药配方颗粒企业重点实验室,广东 佛山 528244 Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China  
邝敏 KUANG Min 广东一方制药有限公司 广东省中药配方颗粒企业重点实验室,广东 佛山 528244 Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China  
林嘉明 LIN Jia-ming 广东一方制药有限公司 广东省中药配方颗粒企业重点实验室,广东 佛山 528244 Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China  
蔡盛康 CAI Sheng-kang 广东一方制药有限公司 广东省中药配方颗粒企业重点实验室,广东 佛山 528244 Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China  
张正* ZHANG Zheng 广东一方制药有限公司 广东省中药配方颗粒企业重点实验室,广东 佛山 528244 Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China  
基金项目:佛山市核心技术攻关项目(1920001000378)
中文摘要:目的 优选醋五灵脂的炮制工艺。方法 建立超高效液相色谱指纹图谱,以醋五灵脂9个共有峰的主成分分析结果及外观性状为综合评价指标,采用正交试验考察米醋用量、电炒锅功率、炒制时间对醋五灵脂炮制工艺的影响,以综合得分为评价依据优选醋五灵脂炮制工艺。结果 醋五灵脂的最佳炮制工艺为每100 g五灵脂使用米醋10 g,电炒锅功率600 W,炒制时长10 min。结论 优选的醋五灵脂炮制工艺稳定可行,可为其饮片质量控制和产业化生产提供参考。
中文关键词:醋五灵脂  炮制工艺  正交试验  主成分分析  超高效液相色谱法指纹图谱
 
Optimization of Processing Technology of Vinegar-processed Trogopterori Faeces by Multi-criteria Weighting Analysis Combined with Orthogonal Test
Abstract:Objective To optimize the processing technology of vinegar-processed Trogopterori Faeces.Methods The ultra-high performance liquid chromatography (UPLC) fingerprint was established. The effects of rice vinegar dosage, frying pan power, and frying time on the processing technology of vinegar-processed Trogopterori Faeces were investigated by the orthogonal test with the principal component analysis (PCA) results of the nine common peaks and appearance traits of vinegar-processed Trogopterori Faeces as comprehensive evaluation indicators. The processing technology of vinegar-processed Trogopterori Faeces was optimized based on the comprehensive score.Results The optimal processing conditions of vinegar-processed Trogopterori Faeces were as following: the amount of rice vinegar of 10 g for 100 g of Trogopterori Faeces, the frying pan powder of 600 W, and the frying time of 10 min.Conclusion The optimal processing technology of vinegar-processed Trogopterori Faeces is stable and feasible, which can provide a reference for the quality control and industrial production of its decoction pieces.
keywords:vinegar-processed Trogopterori Faeces  processing technology  orthogonal test  PCA  UPLC fingerprint
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