| 多指标权重分析法结合正交试验优选醋五灵脂炮制工艺 |
| 投稿时间：2022-02-16 点此下载全文
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| 引用本文：李玲,彭致铖,严玉晶,邝敏,林嘉明,蔡盛康,张正.多指标权重分析法结合正交试验优选醋五灵脂炮制工艺[J].中国现代中药,2022,24(12):2455-2461 |
| DOI：10.13313/j.issn.1673-4890.20220216004 |
| 摘要点击次数: 102 |
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| 作者中文名 | 作者英文名 | 单位中文名 | 单位英文名 | E-Mail |
| 李玲 |
LI Ling |
广东一方制药有限公司 广东省中药配方颗粒企业重点实验室，广东 佛山 528244 |
Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China |
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| 彭致铖 |
PENG Zhi-cheng |
广东一方制药有限公司 广东省中药配方颗粒企业重点实验室，广东 佛山 528244 |
Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China |
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| 严玉晶 |
YAN Yu-jing |
广东一方制药有限公司 广东省中药配方颗粒企业重点实验室，广东 佛山 528244 |
Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China |
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| 邝敏 |
KUANG Min |
广东一方制药有限公司 广东省中药配方颗粒企业重点实验室，广东 佛山 528244 |
Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China |
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| 林嘉明 |
LIN Jia-ming |
广东一方制药有限公司 广东省中药配方颗粒企业重点实验室，广东 佛山 528244 |
Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China |
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| 蔡盛康 |
CAI Sheng-kang |
广东一方制药有限公司 广东省中药配方颗粒企业重点实验室，广东 佛山 528244 |
Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China |
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| 张正* |
ZHANG Zheng |
广东一方制药有限公司 广东省中药配方颗粒企业重点实验室，广东 佛山 528244 |
Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules, Guangdong Efong Pharmaceutical Co., Ltd., Foshan 528244, China |
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| 基金项目:佛山市核心技术攻关项目（1920001000378） |
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| 中文摘要:目的 优选醋五灵脂的炮制工艺。方法 建立超高效液相色谱指纹图谱，以醋五灵脂9个共有峰的主成分分析结果及外观性状为综合评价指标，采用正交试验考察米醋用量、电炒锅功率、炒制时间对醋五灵脂炮制工艺的影响，以综合得分为评价依据优选醋五灵脂炮制工艺。结果 醋五灵脂的最佳炮制工艺为每100 g五灵脂使用米醋10 g，电炒锅功率600 W，炒制时长10 min。结论 优选的醋五灵脂炮制工艺稳定可行，可为其饮片质量控制和产业化生产提供参考。 |
| 中文关键词:醋五灵脂 炮制工艺 正交试验 主成分分析 超高效液相色谱法指纹图谱 |
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| Optimization of Processing Technology of Vinegar-processed Trogopterori Faeces by Multi-criteria Weighting Analysis Combined with Orthogonal Test |
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| Abstract:Objective To optimize the processing technology of vinegar-processed Trogopterori Faeces.Methods The ultra-high performance liquid chromatography (UPLC) fingerprint was established. The effects of rice vinegar dosage, frying pan power, and frying time on the processing technology of vinegar-processed Trogopterori Faeces were investigated by the orthogonal test with the principal component analysis (PCA) results of the nine common peaks and appearance traits of vinegar-processed Trogopterori Faeces as comprehensive evaluation indicators. The processing technology of vinegar-processed Trogopterori Faeces was optimized based on the comprehensive score.Results The optimal processing conditions of vinegar-processed Trogopterori Faeces were as following: the amount of rice vinegar of 10 g for 100 g of Trogopterori Faeces, the frying pan powder of 600 W, and the frying time of 10 min.Conclusion The optimal processing technology of vinegar-processed Trogopterori Faeces is stable and feasible, which can provide a reference for the quality control and industrial production of its decoction pieces. |
| keywords:vinegar-processed Trogopterori Faeces processing technology orthogonal test PCA UPLC fingerprint |
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