多指标结合AHP-CRITIC优化酸枣叶拌蒸酸枣仁炮制工艺
投稿时间:2023-05-26     点此下载全文
引用本文:程世赞,华悦,廉婧,聂紫璇,苏国明,常源,史辑,贾天柱.多指标结合AHP-CRITIC优化酸枣叶拌蒸酸枣仁炮制工艺[J].中国现代中药,2024,26(4):677-684
DOI:10.13313/j.issn.1673-4890.20230526001
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作者中文名作者英文名单位中文名单位英文名E-Mail
程世赞 CHENG Shi-zan 辽宁中医药大学 药学院,辽宁 大连 116600 Liaoning University of Traditional Chinese Medicine School of Pharmacy, Dalian 110600, China  
华悦 HUA Yue 辽宁中医药大学 药学院,辽宁 大连 116600 Liaoning University of Traditional Chinese Medicine School of Pharmacy, Dalian 110600, China  
廉婧 LIAN Jing 辽宁中医药大学 药学院,辽宁 大连 116600 Liaoning University of Traditional Chinese Medicine School of Pharmacy, Dalian 110600, China  
聂紫璇 NIE Zi-xuan 辽宁中医药大学 药学院,辽宁 大连 116600 Liaoning University of Traditional Chinese Medicine School of Pharmacy, Dalian 110600, China  
苏国明 SU Guo-ming 辽宁中医药大学 药学院,辽宁 大连 116600 Liaoning University of Traditional Chinese Medicine School of Pharmacy, Dalian 110600, China  
常源 CHANG Yuan 辽宁中医药大学 药学院,辽宁 大连 116600 Liaoning University of Traditional Chinese Medicine School of Pharmacy, Dalian 110600, China  
史辑* SHI Ji 辽宁中医药大学 药学院,辽宁 大连 116600
辽宁省中药炮制技术产业创新中心,辽宁 大连 116600
Liaoning University of Traditional Chinese Medicine School of Pharmacy, Dalian 110600, China
Liaoning Province Traditional Chinese Medicine Processing Technology Industry Innovation Center, Dalian 110600, China
 
贾天柱 JIA Tian-zhu 辽宁中医药大学 药学院,辽宁 大连 116600
辽宁省中药炮制技术产业创新中心,辽宁 大连 116600
Liaoning University of Traditional Chinese Medicine School of Pharmacy, Dalian 110600, China
Liaoning Province Traditional Chinese Medicine Processing Technology Industry Innovation Center, Dalian 110600, China
 
基金项目:国家自然科学基金项目(81874345);国家中医药管理局重点实验室研究领域的中医临床疗效提升项目(2100222179);沈阳市中青年科技创新人才支持计划项目(RC200174);2022年辽宁省自然科学基金资助面上项目(2022-MS-223)
中文摘要:目的 采用正交设计结合层次分析法-客观赋权法(AHP-CRITIC)优化酸枣叶拌蒸酸枣仁的炮制工艺。方法 采用单因素试验优化辅料酸枣叶的加入倍量和蒸制时间,以酸枣叶的加入倍量和蒸制时间为因素,以斯皮诺素、6?-阿魏酰斯皮诺素、酸枣仁皂苷A、白桦脂酸含量为评价指标进行综合加权评分,结合AHP-CRITIC优化酸枣仁的拌蒸工艺。结果 最佳拌蒸工艺为酸枣叶加入量是酸枣仁的4倍,1层酸枣叶1层酸枣仁交替平铺,上锅蒸制3 h。结论 多指标结合AHP-CRITIC优选酸枣仁拌蒸工艺合理可行,可为酸枣叶拌蒸酸枣仁炮制工艺的生产实践提供参考。
中文关键词:酸枣仁  酸枣叶  拌蒸工艺  正交设计  层次分析法-客观赋权法
 
Optimization of the Co-steaming Process of Semen Ziziphi Spinosae with Ziziphus Jujuba Leaf by Multi-index Combined with AHP-CRITIC Method
Abstract:Objective To optimize the co-steaming process of Semen ziziphi spinosae with Ziziphus jujuba leaf based on orthogonal design and AHP-CRITIC method.Method The single-factor experiment was applied to screen dosage range for Z. jujuba leaf and steaming time. Then, the co-steaming process was optimized by orthogonal design combined with AHP-CRITIC method with the contents of spinosin, 6?-ferulospinosin,jujuboside A, and betulinic acid as evaluation indexes and usage amount of Z. jujuba leaf and steaming time as influencing factors.Results The optimal co-steaming process was to lay the Z. jujuba leaf and Semen ziziphi spinosae alternately, and the usage amount for Z. jujuba leaf was four times that of Semen ziziphi spinosae. The steaming time was 3 hours.Conclusion The orthogonal design combined with AHP-CRITIC method was reasonable and feasible, and could provide a reference for the production practice of co-steaming process of Semen ziziphi spinosae with Z. jujuba leaf.
keywords:Semen ziziphi spinosae  Ziziphus jujuba leaf  co-steaming process  orthogonal design  AHP-CRITIC
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