| Abstract:Objective: To standardize the clinical dispensing technology of traditional Chinese patent medicines containing cinnabar and realgar, clarify the work flow of clinical pharmacists, and guide clinical rational drug use. Methods: Sort out the Chinese Pharmacopoeia (Volume 1, 2020) and the National Essential Drug Catalogue (2018 Edition), establish the "traditional Chinese patent medicines database containing cinnabar and realgar", then analyze the main points and difficulties of traditional Chinese patent medicines containing cinnabar and realgar in the clinical dispensing and use process, in order to build nine key technologies including procurement acceptance technology, storage and maintenance technology, prescription review technology, prescription dispensing technology, drug dispensing and medication guidance techniques, prescription comment technology, drug use monitoring technology and drug use alert technology. Results: According to the correlation evaluation of ADRs adopted in China, 73.53% of ADRs are likely to be caused by traditional Chinese patent medicines containing cinnabar or realgar. The main problems in the course of drug use are long-term, excessive, and over indication drugs. The key links affecting the dispensing of traditional Chinese patent medicines containing cinnabar and realgar include purchase acceptance, storage and maintenance, prescription review, prescription dispensing, prescription review, drug distribution and medication guidance, prescription comment, medication monitoring and medication vigilance. Conclusion: Standardizing the research on the clinical dispensing technology of traditional Chinese patent medicines containing cinnabar and realgar has important practical and guiding significance for standardizing the dispensing technology process that affects the safety of clinical medication, and promoting the high-quality development of clinical pharmaceutical services of Chinese medicine. |
