| Abstract:Ginsenoside has rich pharmacological effects such as regulating immunity, anti-inflammatory, anti fatigue, and stimulating the central nervous system, and is currently widely used in the fields of food and medicine. Ginsenosides can be classified into intrinsic ginsenosides and rare ginsenosides, both of which have the same glycoside structure. The main difference between them is the number of sugar groups connected to the glycoside. Inherent ginsenosides have high content but low activity and are difficult to absorb, while rare ginsenosides have low content but good activity and are easy to absorb. The low content of rare ginsenosides limits their utilization, and converting high content inherent ginsenosides into rare ginsenosides through different methods has become an important approach for preparing rare ginsenosides. The traditional conversion methods mainly include chemical, physical, and microbial conversion methods. The first two have strict requirements for conditions and high preparation costs. Microbial transformation method has the advantages of green environmental protection, low cost, high conversion rate, and high specificity. The author will review the transformation methods of ginsenosides, with a particular focus on microbial transformation methods, to provide ideas and methods for obtaining rare ginsenosides. |
