丹参-三七药对治疗冠心病的药效和机制研究进展 |
投稿时间:2023-11-06 点此下载全文
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引用本文:陶慧娟,王文晓,乐世俊.丹参-三七药对治疗冠心病的药效和机制研究进展[J].中国现代中药,2024,26(5):927-936 |
DOI:10.13313/j.issn.1673-4890.20231106001 |
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基金项目:国家自然科学基金青年科学基金项目(81903786);陕西中医药大学校级科研课题(2023GP24) |
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中文摘要:近些年来,丹参和三七在临床上常被用来治疗冠心病如心肌缺血、动脉粥样硬化,以及与冠心病等危的糖尿病和高血压等。因此,丹参-三七药对及其组分配伍治疗冠心病的潜在机制受到广泛关注。大量文献表明丹参-三七及其组分配伍在治疗冠心病中具有调节脂质代谢和能量代谢、抗炎、抗血小板聚集、改善内皮细胞功能作用。总结了丹参-三七药对及其组分配伍在治疗冠心病中的药效和机制,以期为其后续研究提供更全面的理论依据。 |
中文关键词:丹参 三七 组分配伍 冠心病 |
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Research Progress on Pharmacological Effects and Mechanisms of Salvia miltiorrhiza-Panax notoginseng Herb Pair on Coronary Heart Disease |
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Abstract:In recent years, Salvia Miltiorrhiza and Panax notoginseng are often used clinically to treat coronary heart disease such as myocardial ischemia, atherosclerosis, as well as diabetes and hypertension which are the same health threatening as coronary heart disease. Therefore, the potential mechanism of their herb pair (DQ) and its component compatibility to treat coronary heart disease has received extensive attention. Numerous literature have revealed that DQ and its component compatibility have the effects of regulating lipid metabolism and energy metabolism, anti-inflammatory, anti-platelet aggregation and improving endothelial cell function in the treatment of coronary heart disease. This paper summarized the pharmacological effects and mechanisms of DQ and its component compatibility, so as to provide a comprehensively theoretical basis for subsequent research of DQ. |
keywords:Salvia miltiorrhiza Bge. Panax notoginseng (Burk.) F. H. Chen component compatibility coronary heart disease |
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