| Abstract:Objective:The combination of multi-indicator comprehensive weighted scoring method is used to combine the response surface test,and the best extraction process for promoting the Xuandao Xiefei decoction preferred agents.Methods:In order to effectively improve the extraction process of the agent,a model optimization model based on game theory combination empowerment is proposed.It uses the G1 method and the EWM method to calculate the subjective weight of the evaluation index,and the best combination weight is introduced to the game theory.Using the contents of Sinapine cyanide sulfonate,Amygdalin,Hesperidin,Ferulic Acid and ratio of dry extraction as comprehensive evaluation indicators,through single factor tests and Box-Behnken response surface method to investigate the influence of the water addition,soaking time and extraction time of the water extraction process of XDXF decoction to optimize extraction process parameters.Results:The comprehensive score is performed according to the weight of each indicator determined by the combination weighting method to determine the optimal extraction process parameters of XDXF decoction,as adding 10 times of the amount of water,soaking time for 44 minutes,extracting 3 times,total time for 160 minutes.The verification test results show that compared with the measured value,the RSD of the predicted value was≤3%.Conclusion:After the optimization,the extraction of process parameters is verified,which has good stability and repetitiveness,which lays the foundation for subsequent research of XDXF decoction. |
