天山雪莲化学成分、药理活性研究进展及Q-Marker预测
投稿时间:2024-08-29  修订日期:2024-11-21   点此下载全文
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作者中文名作者英文名单位中文名单位英文名E-Mail
刘佩姿 LIU Pei-zi 湖南医药学院药学院 College of pharmacy,Hunan University of Medicine 18522650390@163.com 
张贤睿 ZHANG Xian-rui 中国药科大学 China Pharmaceutical University 250185228@qq.com 
陈可怡 CHEN Ke-yi 湖南医药学院药学院 College of pharmacy,Hunan University of Medicine 19973213436@163.com 
张岩岩 ZHANG Yan-yan 新疆农业大学食品科学与药学学院 College of Food Science and Pharmacy,Xinjiang Agricultural University zhangyanyan9527@163.com 
苗莉娟 MIAO Li-juan 新疆天山雪莲制药有限公司 Xinjiang Tianshan Xuelian Pharmaceutical Co,Ltd 429635912@qq.com 
王新宇 WANG Xin-yu 新疆天山雪莲制药有限公司 Xinjiang Tianshan Xuelian Pharmaceutical Co,Ltd 892065658@qq.com 
蔡伟* CAI Wei 湖南医药学院药学院 College of pharmacy,Hunan University of Medicine 20120941161@bucm.edu.cn 
基金项目:新疆维吾尔自治区“十四五”重大科技专项(2022A03003)
中文摘要:天山雪莲是我国传统中药材之一,主要分布于中国西部高原地区,在我国少数民族地区广泛使用。通过高效液相色谱法、阴离子交换和凝胶渗透柱色谱等方法,已从天山雪莲中分离出多种化合物,包括黄酮、倍半萜内酯及其苷、苯丙素、多糖、木脂素等类。天山雪莲有抗炎镇痛、保护神经、抗肿瘤、抗辐射、抗肥胖、免疫调节等药理作用。对近年来天山雪莲的研究进展进行综述,并对其质量标志物进行预测,为其深入研究和应用提供参考。
中文关键词:天山雪莲  化学成分  药理活性
 
Research progress on chemical constituents and pharmacological activity of Saussurea involucrata and Q-Marker prediction
Abstract:Saussurea involucrata is one of the traditional Chinese herbal medicines, mainly distributed in the western highland areas of China, and widely used in the ethnic minority areas of China. Through methods such as high-performance liquid chromatography, anion exchange and gel permeation chromatography, various compounds have been isolated from the snowdrop lily, including flavonoids, sesquiterpenoid lactones and their glycosides, phenylpropanoids, polysaccharides, and lignans. The Saussurea involucrata has pharmacological effects such as anti-inflammatory and analgesic, protection of nerves, anti-tumor, anti-radiation, anti-obesity and immune regulation. The research progress of Saussurea involucrata in recent years was reviewed, and its quality markers were predicted to provide reference for its further study and application.
keywords:Saussurea involucrata  chemical composition  pharmacological activity.Q-marker
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