| 天山雪莲化学成分、药理活性研究进展及Q-Marker预测 |
| 投稿时间：2024-08-29 修订日期：2024-09-27 点此下载全文
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| 基金项目:新疆维吾尔自治区“十四五”重大科技专项(2022A03003) |
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| 中文摘要:天山雪莲是我国传统中药材之一,主要分布于中国西部高原地区,广泛运用于我国少数民族地区。通过高效液相色谱法、阴离子交换和凝胶渗透柱色谱等方法,已从天山雪莲分离出多种化合物,其主要的化学成分包括黄酮类、倍半萜内酯及其苷类、苯丙素类、多糖类、木脂素类等。天山雪莲有抗炎镇痛、保护神经、抗肿瘤、抗辐射、抗肥胖、免疫调节等功效。本篇综述旨在总结近年来对于天山雪莲的研究进展,为进一步深入研究天山雪莲提供参考,推动其发展和应用。 |
| 中文关键词:天山雪莲 化学成分 药理活性 |
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| Research progress on chemical constituents and pharmacological activity of Saussurea involucrata and Q-Marker prediction |
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| Abstract:Saussurea involucrata, commonly known as Snow Lotus and traditionally used in Chinese medicine, predominantly thrives in the high-altitude regions of Western China and is widely utilized in the ethnically diverse areas of the country. Through methodologies such as High-Performance Liquid Chromatography (HPLC), anion exchange, and gel permeation chromatography, several compounds have been isolated from Snow Lotus. Its principal chemical constituents include flavonoids, sesquiterpene lactones and their glycosides, phenylpropanoids, polysaccharides, and lignans. The therapeutic properties of Snow Lotus encompass anti-inflammatory and analgesic effects, neuroprotection, anti-tumor, radiation protection, anti-obesity, and immunomodulation. This review aims to summarize the recent research advancements on Saussurea involucrata, providing a reference for further in-depth studies and promoting its development and application. |
| keywords:Saussurea involucrata chemical composition pharmacological activity. |
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