农药残留快速检测技术的研究进展及在中药中农残检测中的应用
投稿时间:2024-10-08  修订日期:2024-10-18   点此下载全文
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作者中文名作者英文名单位中文名单位英文名E-Mail
周婷婷 zhoutingting 中国药科大学中药学院 China Pharmaceutical University School of Traditional Chinese Pharmacy 870954263@qq.com 
王莹* WANGYING 中国食品药品检定研究院 China Institute for Food and Drug Control wayi_1986@163.com 
中文摘要:农药的现代检测技术包括气相色谱法、液相色谱法、气相色谱-质谱联用法、液相色谱-质谱联用法等。现代色谱仪器分析方法因其成本较高、前处理复杂、设备庞大、检测时间长等特点难以满足基层大批量药材快速筛查的需求。因此,发展简单、快速、便携、高通量的农残分析方法对我国中药质量安全监管与生产过程控制具有十分重要的意义。本文重点介绍了光谱法、酶抑制法、免疫分析技术、电化学生物传感器、高分辨质谱等农残快检技术的应用及发展现状。同时,近些年来中药中农残问题受到社会广泛关注,农残标准方法不断完善。针对中药生产特点,在现有的中药农残标准体系下,补充中药中农残快检技术对于中药材全链条安全监控、降低检测成本、促进产业发展有重要意义。然而现有中药中快检技术发展相较于食品较为缓慢,本综述对目前中药中农残快检技术发展趋势进行分析,以期为中药中农残快检技术的快速发展提供参考。
中文关键词:农药残留  快速检测  光谱法  免疫学  中药
 
Research Progress of Pesticide Residue Rapid Detection Technology and its Application in the Detection of Pesticide Residues in Traditional Chinese Medicine
Abstract:Modern detection techniques for pesticides include gas chromatography, liquid chromatography, gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry. The modern chromatographic instrumental analytical methods are difficult to meet the demand for rapid screening of large quantities of traditional Chinese medicine (TCM) at the community-level due to their high cost, complex pre-treatment, bulky equipment and long detection time. Therefore, the development of simple, rapid, portable and high-throughput pesticide residue analysis methods is important to the quality and safety supervision and production process control of TCM in China. This paper focuses on the application and development status of pesticide residue rapid detection techniques such as spectrometry, enzyme inhibition, immunoassay technology, electrochemical biosensors, and high-resolution mass spectrometry. Meanwhile, the pesticide residues in TCM have been widely concerned by the society in recent years, and the standard methods for pesticide residues have been improved continuously. In view of the production characteristics of TCM, under the existing pesticide residue standard system of TCM, it is important to supplement the pesticide residue rapid detection technology for the whole chain safety monitoring of TCM, reduce the cost of detection, and promote the development of the industry. However, the development of the existing rapid detection technology in TCM is relatively slow compared with that of food, and this review analyses the current development trend of pesticide residue rapid detection technology in TCM, in order to provide a reference for the rapid development of pesticide rapid detection technology in TCM.
keywords:pesticide residues  rapid detection  spectroscopy  immunology  traditional Chinese medicine
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